Cytokeratin Pan Type II Antibodies

Target Information

Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Synonyms

2310016L08Rik; 3300001P10Rik; 57kd keratin; 57kDa keratin; 58 kDa cytokeratin; 60-kDa keratin; 65 kDa cytokeratin; 67 kDa cytokeratin; AA960620; AI507495; AL022697; AU019895; AW108092; AW146334; BB005427; CARD2; CK 2e; CK1; CK-1; CK-2e; CK3; CK-3; CK4; CK-4; CK5; CK-5; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; CK7; CK-7; CK-72; CK8; CK-8; CYK4; CYK8; CYKER; cytokeratin 1; cytokeratin 3; cytokeratin 4; cytokeratin 5; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin 7; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; Cytokeratin otokeratin; cytokeratin type II, component Ib/c; cytokeratin type II, component III; cytokeratin-1; Cytokeratin-2e; cytokeratin-3; Cytokeratin-4; cytokeratin-5; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; cytokeratin-7; Cytokeratin-72; cytokeratin-8; Cytokeratin-A; cytoskeletal 57 kDa keratin; D15Wsu77e; DDD; DDD1; EBS2; EGK_03684; EGK_03685; EHK; EHK1; EndoA; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; epidermolytic hyperkeratosis 1; epithelial keratin 1; epithelial keratin 2e; epithelial keratin-1; Epithelial keratin-2e; EPPK; Hair alpha protein; Hom s 5; K1; K2C7; K2C8; K2E; K3; K3 keratin; K4; K5; K6A; K6C; K6D; K6irs; K6IRS2; K7; K72; K8; kamp-keratin derived antimicrobial peptide; Kb1; Kb2; Kb35; Kb4; Kb7; KDAMP; KER1; Ker2; KERA; keratin; keratin 1; keratin 1 (epidermolytic hyperkeratosis); keratin 1, type II; keratin 2; keratin 2 (epidermal ichthyosis bullosa of Siemens); keratin 2 epidermis; keratin 2, type II; keratin 2A; keratin 2A (epidermal ichthyosis bullosa of Siemens); keratin 3; keratin 3, type II; keratin 4; keratin 4, type II; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 5-like; keratin 6 alpha; keratin 6, inner root sheath, 2; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin 6A-like; keratin 6B; keratin 7; keratin 7, type II; keratin 72; keratin 72, pseudogene; keratin 72, type II; keratin 75; keratin 8; keratin 8, type II; keratin 86; keratin complex 2, basic, gene 1; keratin complex 2, basic, gene 17; keratin complex 2, basic, gene 35; keratin complex 2, basic, gene 4; keratin complex 2, basic, gene 5; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, basic, gene 7; keratin complex 2, basic, gene 8; keratin complex 2, gene 17; keratin complex 2, gene 6a; keratin IV; keratin K3; keratin K6h; keratin protein K6irs; keratin, 55K type II cytoskeletal; keratin, epidermal type II, K6A; keratin, simple epithelial type I, K7; keratin, type II cytoskeletal 1; Keratin, type II cytoskeletal 2 epidermal; keratin, type II cytoskeletal 3; Keratin, type II cytoskeletal 4; keratin, type II cytoskeletal 5; keratin, type II cytoskeletal 59 kDa, component IV; keratin, type II cytoskeletal 60 kDa, component III; keratin, type II cytoskeletal 6A; keratin, type II cytoskeletal 6C; keratin, type II cytoskeletal 7; Keratin, type II cytoskeletal 72; keratin, type II cytoskeletal 8; Keratin, type II cytoskeletal cochleal; keratin-1; Keratin-2 epidermis; Keratin-2e; Keratin-3; Keratin-4; keratin-5; keratin-6A; Keratin-6-alpha; keratin-6C; keratin-7; Keratin-72; keratin-8; KERIB; KO; Krt1; krt1 {ECO:0000250; KRT1A; Krt2; krt2 {ECO:0000250; Krt-2.1; Krt-2.4; Krt-2.8; Krt2-1; Krt2-17; Krt2-2; Krt2-35; Krt2-4; Krt2-5; Krt2-6; Krt2-6a; Krt2-6c; Krt2-7; Krt2-8; KRT2A; KRT2E; KRT3; Krt4; krt4 {ECO:0000250; Krt5; KRT5A; KRT6; KRT6A; KRT6B; KRT6C; KRT6D; KRT6IRS2; KRT7; krt7 {ECO:0000250; Krt72; Krt72-ps; KRT75; Krt8; Krt86; KRTA; KRTE; LOC100352658; LOC100353415; LOC486523; MGC116967; MGC116968; mK6[a]; MK6a; mK6-alpha; NEPPK; otokeratin; pan keratin; PC3; Sak57; Sarcolectin; SCL; similar to keratin 7; Tfip8; tuftelin interacting protein 8; type II alpha keratin IIA; type II alpha-keratin IIC; type II cytokeratin A (no.8)